The Smit-Caple DSAC Pauson-Khand cyclization of a series of N-protected allyl propargyl amines in the absence of oxygen gave rise to formation of the saturated azabicyclo[3.3.0]octanones in excellent yields. Standard cyclization in air gave mixtures of saturated and unsaturated ketones.
Becker, Daniel and Flynn, Daniel L.. Studies of the Solid-Phase Pauson-Khand Reaction Selective in-situ Enone Reduction to 3-Azabicyclo[3.3.0]oct-anones. Tetrahedron Letters, 34, 13: , 1993. Retrieved from Loyola eCommons, Chemistry: Faculty Publications and Other Works, http://dx.doi.org/10.1016/S0040-4039(00)60352-0
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