Document Type
Article
Publication Date
6-4-1993
Publication Title
Tetrahedron Letters
Volume
49
Issue
23
Pages
5047-5054
Publisher Name
Elsevier
Abstract
An intramolecular reductive Pauson-Khand reaction of the hexacarbonyldicobalt complex of N-(tert-butyloxycarbonyl)allylpropargylamine under dry-state adsorption conditions directly afforded the saturated N-BOC-3-azabicyclo[3.3.0]octan-7-one when the reaction was performed under an inert atmosphere. This bicyclic ketone was converted in several steps to the novel octahydro-1-azeto[2′,3′:3,4]cyclopenta[1,2-C]pyrrole ring system as confirmed by single crystal X-ray analysis.
Recommended Citation
Becker, Daniel and Flynn, Daniel L.. Synthesis of N-BOC-3-azabicyclo[3.3.0]octan-7-one via reductive pauson-khand cyclization and subsequent conversion to a novel diazatricyclic ring system. Tetrahedron Letters, 49, 23: 5047-5054, 1993. Retrieved from Loyola eCommons, Chemistry: Faculty Publications and Other Works, http://dx.doi.org/10.1016/S0040-4020(01)81870-6
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Copyright Statement
© 1993 Elsevier
Comments
Author Posting © Elsevier, 1993. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution. The definitive version was published in Tetrahedron, Volume 49, Issue 23, June 4, 1993. http://dx.doi.org/10.1016/S0040-4020(01)81870-6