Title

Selective, Orally Active MMP Inhibitors with an Aryl Backbone

Document Type

Article

Publication Date

9-17-2001

Publication Title

Bioorganic & Medicinal Chemistry Letters

Volume

11

Issue

18

Abstract

This letter describes SAR exploration and rat PK optimization of a series of novel, MMP-1 sparing aryl hydroxamate sulfonamides with activity against MMP-2 and MMP-13.

Comments

Author Posting © Elsevier, 2001. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution. The definitive version was published in Bioorganic & Medicinal Chemistry Letters, Volume 11, Issue 18, September 17, http://dx.doi.org/10.1016/S0960-894X(01)00487-5

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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