Selective, Orally Active MMP Inhibitors with an Aryl Backbone
Document Type
Article
Publication Date
9-17-2001
Publication Title
Bioorganic & Medicinal Chemistry Letters
Volume
11
Issue
18
Pages
2481-2483
Publisher Name
Elsevier
Abstract
This letter describes SAR exploration and rat PK optimization of a series of novel, MMP-1 sparing aryl hydroxamate sulfonamides with activity against MMP-2 and MMP-13.
Recommended Citation
Barta, Thomas; Becker, Daniel P.; Bedell, Louis J.; and De Crescenzo, Gary A.. Selective, Orally Active MMP Inhibitors with an Aryl Backbone. Bioorganic & Medicinal Chemistry Letters, 11, 18: 2481-2483, 2001. Retrieved from Loyola eCommons, Chemistry: Faculty Publications and Other Works, http://dx.doi.org/10.1016/S0960-894X(01)00487-5
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Copyright Statement
© 2001 Elsevier
Comments
Author Posting © Elsevier, 2001. The definitive version was published in Bioorganic & Medicinal Chemistry Letters, Volume 11, Issue 18, September 17, http://dx.doi.org/10.1016/S0960-894X(01)00487-5