Synthesis of Substituted 2-Amino-Cyclobutanones

Authors

Nicola Armoush, Loyola University Chicago
Preeti Syal
Daniel P. Becker, Loyola University ChicagoFollow

Document Type

Article

Publication Date

5-9-2008

Publication Title

Synthetic Communications

Volume

38

Issue

11

Pages

1679-1687

Publisher Name

Taylor & Francis

Abstract

A series of weakly nucleophilic nitrogen derivatives including carbamates, amides, sulfonamides, and anilines were reacted with 1,2‐bis(trimethylsilyloxy)cyclobutene under acidic conditions to afford various substituted 2‐aminocyclobutanone derivatives 3a–i in modest to excellent yields.

Comments

This is an Author's Accepted Manuscript of an article published in Synthetic Communications, Volume 38, Issue 11, 2008 © Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/00397910801981110

Recommended Citation

Armoush, Nicola; Syal, Preeti; and Becker, Daniel P.. Synthesis of Substituted 2-Amino-Cyclobutanones. Synthetic Communications, 38, 11: 1679-1687, 2008. Retrieved from Loyola eCommons, Chemistry: Faculty Publications and Other Works, http://dx.doi.org/10.1080/00397910801981110

Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

Copyright Statement

© 2008 Taylor & Francis