Major
Chemistry
Anticipated Graduation Year
2024
Access Type
Open Access
Abstract
Our laboratory is interested in understanding the role of Type II alpha 1 collagen (Col2a1) in vertebrate development. We utilize Danio rerio, the common zebrafish, to elucidate the function of the zebrafish version of the gene. Our goal is to visualize and locate the presence of the type II alpha 1 collagen b gene (col2a1b) in zebrafish. col2a1b's collagen expression occurs solely in the perichondrium, while its parlor, col2a1a, is expressed in chondrocytes and in the perichondrium. We also aim to discover how the col2a1b gene maintains its expression in the perichondrium using in situ hybridization.
Faculty Mentors & Instructors
Dr. Rodney M. Dale, associate professor, Department of Biology
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Expression of mRNA of the col2a1b gene during Zebrafish Embryogenesis
Our laboratory is interested in understanding the role of Type II alpha 1 collagen (Col2a1) in vertebrate development. We utilize Danio rerio, the common zebrafish, to elucidate the function of the zebrafish version of the gene. Our goal is to visualize and locate the presence of the type II alpha 1 collagen b gene (col2a1b) in zebrafish. col2a1b's collagen expression occurs solely in the perichondrium, while its parlor, col2a1a, is expressed in chondrocytes and in the perichondrium. We also aim to discover how the col2a1b gene maintains its expression in the perichondrium using in situ hybridization.