Major
Biology
Anticipated Graduation Year
2023
Access Type
Open Access
Abstract
Our laboratory is interested in understanding the role of Type II alpha 1 collagen (Col2a1) in vertebrate development. We utilize Danio rerio, the common zebrafish, to elucidate the function of the zebrafish version of this gene. Our goal is to visualize and locate the presence of the type II alpha 1 collagen b gene (col2a1b) in zebrafish. col2a1b's collagen expression occurs solely in the perichondrium, while its paralog, col2a1a, is expressed in chondrocytes and in the perichondrium. A goal of our project is to discover how the col2a1b gene maintains its expression in the perichondrium using in situ hybridization.
Faculty Mentors & Instructors
Dr. Rodney M. Dale, Department of Biology
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Expression of mRNA of the col2a1b gene during Zebrafish Embryogenesis
Our laboratory is interested in understanding the role of Type II alpha 1 collagen (Col2a1) in vertebrate development. We utilize Danio rerio, the common zebrafish, to elucidate the function of the zebrafish version of this gene. Our goal is to visualize and locate the presence of the type II alpha 1 collagen b gene (col2a1b) in zebrafish. col2a1b's collagen expression occurs solely in the perichondrium, while its paralog, col2a1a, is expressed in chondrocytes and in the perichondrium. A goal of our project is to discover how the col2a1b gene maintains its expression in the perichondrium using in situ hybridization.