Major
Biology
Anticipated Graduation Year
2024
Access Type
Restricted Access
Abstract
The epidemic of obesity has been affecting individuals globally, with roughly 650 million adults obese in 2016 (WHO, 2021). According to the Centers for Disease Control and Prevention (CDC), obesity increases the risk of multiple life-threatening diseases such as stroke, high blood pressure, coronary artery disease, and overall results in a reduced standard of living. In this study, we manipulate animals’ diets with isocaloric high- (42% of kcals from fat) and low-fat (15% kcals from fat) diets. Here we report on the genetic basis for variation in fat depots, in levels of sexual dimorphism, and in dietary response, as well as finding the genomic locations associated with the variation of the fat depots.
Community Partners
Cura Scholars
Faculty Mentors & Instructors
Fernando Cipriano Andrade Oliveria; Dr. James Cheverud
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Genetic Variation in Fat Depot Weights in Mice
The epidemic of obesity has been affecting individuals globally, with roughly 650 million adults obese in 2016 (WHO, 2021). According to the Centers for Disease Control and Prevention (CDC), obesity increases the risk of multiple life-threatening diseases such as stroke, high blood pressure, coronary artery disease, and overall results in a reduced standard of living. In this study, we manipulate animals’ diets with isocaloric high- (42% of kcals from fat) and low-fat (15% kcals from fat) diets. Here we report on the genetic basis for variation in fat depots, in levels of sexual dimorphism, and in dietary response, as well as finding the genomic locations associated with the variation of the fat depots.