Major
Chemistry
Anticipated Graduation Year
2024
Access Type
Restricted Access
Abstract
The protein Ribbon (Rib) has been identified as a novel transcription factor in the somatic follicle cells of Drosophila ovaries. During the process of oogenesis, follicle stem cells replicate and mitotically divide to form a protective epithelial sheath around the developing oocyte and nurse cells. Throughout this process somatic cells and germ cells communicate to coordinate their development for the production of a mature egg. In order to study the role of Rib in oogenesis, we are using clonal analysis and RNAi to determine the effect of reduced levels of Rib on oocyte development in female ovaries of Drosophila melanogaster.
Faculty Mentors & Instructors
Dr. Jennifer Mierisch, Biology Assistant Professor
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Clonal Analysis of rib Mutants In Follicle Cells of Drosophila Ovaries
The protein Ribbon (Rib) has been identified as a novel transcription factor in the somatic follicle cells of Drosophila ovaries. During the process of oogenesis, follicle stem cells replicate and mitotically divide to form a protective epithelial sheath around the developing oocyte and nurse cells. Throughout this process somatic cells and germ cells communicate to coordinate their development for the production of a mature egg. In order to study the role of Rib in oogenesis, we are using clonal analysis and RNAi to determine the effect of reduced levels of Rib on oocyte development in female ovaries of Drosophila melanogaster.