Document Type

Article

Publication Date

8-2015

Publication Title

Tetrahedron Letters

Volume

56

Issue

40

Pages

5390-5392

Abstract

A cascade reaction sequence involving a Beckmann rearrangement on benzophenone oxime followed by an electrophilic aromatic substitution (EAS) on the intermediate nitrilium ion affords N-phenyl diaryl imines that may then be hydrolyzed to ketones, or reduced to the corresponding amines. Reaction with benzonitrile afforded 2,4-diphenylquinazoline through a Beckmann–Ritter–EAS cascade.

Comments

Author Posting. © Elsevier Ltd. 2015. This article is posted here by permission of Elsevier for personal use, not for redistribution. The article was published in Tetrahedron Letters, vol. 60, no. 40, 2015, https://doi.org/10.1016/j.tetlet.2015.07.095.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

Share

COinS