"Genetic and environmental variation impact transferability of polygeni" by Daniel S. Araújo and Heather E. Wheeler
 

Document Type

Article

Publication Date

7-19-2022

Publication Title

Cell Reports Medicine

Volume

3

Issue

7

Pages

1-3

Publisher Name

Cell Press

Abstract

Even when polygenic risk scores (PRSs) are trained in African ancestral populations, Kamiza and colleagues showed that genetic and environmental variation within sub-Saharan African populations impacts prediction performance, highlighting the challenges of clinical implementation of PRSs for risk assessment.

Identifier

85134772440 (Scopus)

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