Document Type
Article
Publication Date
12-1-2021
Publication Title
Liver Research
Volume
5
Issue
4
Pages
195-203
Publisher Name
KeAi Publishing
Abstract
Hepatocellular carcinoma (HCC) is a very deadly disease. HCC initiation and progression involve multiple genetic events, including the activation of proto-oncogenes and disruption of the function of specific tumor suppressor genes. Activation of oncogenes stimulates cell growth and survival, while loss-of-function mutations of tumor suppressor genes result in unrestrained cell growth. In this review, we summarize the new findings that identified novel proto-oncogenes and tumor suppressors in HCC over the past five years. These findings may inspire the development of novel therapeutic strategies to improve the outcome of HCC patients.
Identifier
85112117755 (Scopus)
Recommended Citation
Wang, Fang; Breslin S J, Peter; and Qiu, Wei. Novel oncogenes and tumor suppressor genes in hepatocellular carcinoma. Liver Research, 5, 4: 195-203, 2021. Retrieved from Loyola eCommons, Biology: Faculty Publications and Other Works, http://dx.doi.org/10.1016/j.livres.2021.06.001
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
