Document Type
Article
Publication Date
5-18-2024
Publication Title
Transplant Infectious Disease
Volume
26
Issue
3
Pages
1-9
Publisher Name
Wiley Periodicals LLC
Abstract
Background: Though the use of Hepatitis B viremic (HBV) donor kidneys may be a safe alternative to improve access to transplantation, there has not been wide acceptance of this practice. In this study, we determined the safety and effectiveness of HBV NAT (+) donor kidneys in a protocolized manner in an older adult population.
Methods: Over a 3-year period, 16 decreased donor kidney transplants were performed with HBV NAT+ kidneys. Recipients of HBV NAT+ kidneys were treated with entecavir started pre-operatively and continued for 52 weeks.
Results: HBV NAT+ kidneys were preferentially used in older (68 ± 5 vs. 64 ± 9 years; p = .01) recipients with less dialysis time (93.8% < 5 years vs. 67% .05).
Conclusion: Transplants with HBV NAT+ donor kidneys in a pre-emptive treatment protocol allow for increased safe access to transplantation in older adult recipients with little or no dialysis time.
Recommended Citation
Lopez-Soler, Reynold I.; Joyce, Cara; Cotiguala, Laura; Aguirre, Oswaldo; Samra, Manpreet; Trotter, Christine; Zingraf, Geraldine; Sorensen, Jeffrey; Sodhi, Rupinder; and Thorndyke, Anne, "Utilization of Hepatitis B viremic donors (NAT+) leads to improved kidney transplant access for older adult recipients with little to no wait time" (2024). Biostatistics Collaborative Core: Faculty Publications and Other Works. 19.
https://ecommons.luc.edu/biostatistics_facpubs/19
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Copyright Statement
© The Author(s), 2024.
Comments
Author Posting © The Author(s), 2024. This article is posted here by permission of Wiley Periodicals LLC for personal use. This article was published open access in Transplant Infectious Disease, Vol. 26, Iss. 3 (June 2024), https://doi.org/10.1111/tid.14295.