Document Type
Article
Publication Date
12-18-2019
Publication Title
Science Advances
Volume
5
Issue
12
Pages
1-8
Publisher Name
American Association for the Advancement of Science
Abstract
Children’s metabolic energy expenditure is central to evolutionary and epidemiological frameworks for understanding variation in human phenotype and health. Nonetheless, the impact of a physically active lifestyle and heavy burden of infectious disease on child metabolism remains unclear. Using energetic, activity, and biomarker measures, we show that Shuar forager-horticulturalist children of Amazonian Ecuador are ~25% more physically active and, in association with immune activity, have ~20% greater resting energy expenditure than children from industrial populations. Despite these differences, Shuar children’s total daily energy expenditure, measured using doubly labeled water, is indistinguishable from industrialized counterparts. Trade-offs in energy allocation between competing physiological tasks, within a constrained energy budget, appear to shape childhood phenotypic variation (e.g., patterns of growth). These trade-offs may contribute to the lifetime obesity and metabolic health disparities that emerge during rapid economic development.
Recommended Citation
Urlacher, Samuel S.; Snodgrass, J. Josh; Dugas, Lara R.; Sugiyama, Lawrence S.; and Liebert, Melissa A., "Constraint and trade-offs regulate energy expenditure during childhood" (2019). Biostatistics Collaborative Core: Faculty Publications and Other Works. 42.
https://ecommons.luc.edu/biostatistics_facpubs/42
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Copyright Statement
© The Author(s), 2019.
Comments
Author Posting © The Author(s), 2019. This article is posted here by permission of the American Association for the Advancement of Science for personal use and non-commercial redistribution. This article was published open access in Science Advances, Vol. 5, Iss. 12 (December 18, 2019), https://doi.org/10.1126/sciadv.aax1065.