Studies of the Solid-Phase Pauson-Khand Reaction Selective in-situ Enone Reduction to 3-Azabicyclo[3.3.0]oct-anones

Authors

Daniel Becker, Loyola University ChicagoFollow
Daniel L. Flynn

Document Type

Article

Publication Date

3-26-1993

Publication Title

Tetrahedron Letters

Volume

34

Issue

13

Pages

2087-2090

Publisher Name

Elsevier

Abstract

The Smit-Caple DSAC Pauson-Khand cyclization of a series of N-protected allyl propargyl amines in the absence of oxygen gave rise to formation of the saturated azabicyclo[3.3.0]octanones in excellent yields. Standard cyclization in air gave mixtures of saturated and unsaturated ketones.

Comments

Author Posting © Elsevier, 1993. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution. The definitive version was published in Tetrahedron Letters, Volume 34, Issue 13, March 26, 1993. http://dx.doi.org/10.1016/S0040-4039(00)60352-0

Recommended Citation

Becker, Daniel and Flynn, Daniel L.. Studies of the Solid-Phase Pauson-Khand Reaction Selective in-situ Enone Reduction to 3-Azabicyclo[3.3.0]oct-anones. Tetrahedron Letters, 34, 13: 2087-2090, 1993. Retrieved from Loyola eCommons, Chemistry: Faculty Publications and Other Works, http://dx.doi.org/10.1016/S0040-4039(00)60352-0

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Copyright Statement

© 1993 Elsevier