Document Type
Article
Publication Date
1-6-1997
Publication Title
Tetrahedron
Volume
53
Issue
1
Pages
1-20
Publisher Name
Elsevier
Abstract
The amino azanoradamantane hexahydro-2,5b-methano-IH-3aS,3aa,6aa-cyclopenta-[clpyrrole-4a-amine 1and the corresponding enantiomer ent-1 have been prepared along with benzamide derivatives SC-52491and SC-52490, respectively, which are of pharmaceutical interest. The key meso-azabicyclo[3.3.0] intermediate 3 was prepared via three separate routes: a [3+2] cycloaddition route, a radical cyclization/ionic cyclization route, and a reductive Pauson-Khand route.
Recommended Citation
Becker, Daniel; Nosal, Roger; Zabrowski, Daniel L.; and Flynn, Daniel. Synthetic Strategies for the Construction of Enantiomeric Azanoradamantanes. Tetrahedron, 53, 1: 1-20, 1997. Retrieved from Loyola eCommons, Chemistry: Faculty Publications and Other Works, http://dx.doi.org/10.1016/S0040-4020(96)00973-8
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Copyright Statement
© 1997 Elsevier
Comments
Author Posting © Elsevier, 1997. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution. The definitive version was published in Tetrahedron, Volume 53, Issue 1, January 6, 1997. http://dx.doi.org/10.1016/S0040-4020(96)00973-8