Document Type
Article
Publication Date
9-9-1997
Publication Title
Bioorganic & Medicinal Chemistry Letters
Volume
17
Issue
1
Pages
2149-2154
Publisher Name
Elsevier
Abstract
A series of meso-amino(methyl)azanoradamantane benzamides has been prepared and evaluated for 5-HT4agonism activity in the rat tunica muscularis mucosae (TMM) assay. Compound 8i is the most potent 5-HT4agonist in the series, with an EC50 of 217 nM.
Recommended Citation
Becker, Daniel; Nosal, Roger; Villamil, Clara I.; and Gullikson, Gary. Serotonin 5-HT4 Agonist Activity of a Series of Meso-Azanoradamantane Benzamides. Bioorganic & Medicinal Chemistry Letters, 17, 1: 2149-2154, 1997. Retrieved from Loyola eCommons, Chemistry: Faculty Publications and Other Works, http://dx.doi.org/10.1016/S0960-894X(97)00408-3
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Copyright Statement
© 1997 Elsevier
Comments
Author Posting © Elsevier, 1997. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution. The definitive version was published in Bioorganic & Medicinal Chemistry Letters, Volume 7, Issue 17, September 9, 1997. http://dx.doi.org/10.1016/S0960-894X(97)00408-3