Date of Award
2020
Degree Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Department
Chemistry
Abstract
The utilization of Lewis acids to activate substrates containing carbonyls is ubiquitous in organic synthetic methods. in order to facilitate the development of novel reaction pathways and understand existing methods, it is necessary to determine the solution interactions between Lewis acids and Lewis bases. Historically, the characterization of the interactions of Lewis pairs has relied on solid state infrared (IR) spectroscopy and X-ray crystallography, as well as in situ NMR. I have developed a method utilizing in situ IR spectroscopy and solution conductivity towards the identification of the solution structures formed when a range of carbonyl compounds are combined with catalytically-active metal halide Lewis acids under synthetically relevant conditions. Experiments designed to elucidate the relevant Lewis acid-carbonyl solution structures to specify their impact in catalytic methods will be presented.
Recommended Citation
Hanson, Carly Soren, "Lewis Acid-Carbonyl Solution Interactions and Their Implications in Catalytic Systems" (2020). Dissertations. 3793.
https://ecommons.luc.edu/luc_diss/3793
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Copyright Statement
Copyright © 2020 Carly Soren Hanson
