Date of Award

Fall 9-8-2025

Degree Type

Thesis

Degree Name

Master of Science (MS)

Department

Biology

First Advisor

Catherine Putonti

Abstract

To explore the relationship between two recently identified bacterial species (S. anginosus and S. urinae), three aims were designed. First, niche ranges were identified via two metagenome databases. Different niche ranges were identified between the two groups. S. urinae was more specific to the urogenital tract. S. anginosus appeared to be present across human anatomical niches. Secondly, specific genes to the S. urinae group were identified. This gives insight into the genomic and phenotypic differences previously identified. Thirdly, a temporal study was created to view S. urinae in female urine over 8 weeks. This showed stability in the urinary microbiome as well as within the S. urinae population in urine. This thesis furthers insight into the divergence of bacteria within the human microbiome and into the temporal dynamics of said bacteria.

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