Document Type
Article
Publication Date
6-15-2010
Publication Title
Bioorganic & Medicinal Chemistry Letters
Volume
20
Issue
12
Pages
3561-3564
Publisher Name
Elsevier
Abstract
A series of N-aryl isonipecotamide α-sulfone hydroxamate derivatives has been prepared utilizing a combination of solution-phase and resin-bound library technologies to afford compounds that are potent and highly selective for MMP-13.
Recommended Citation
Kolodziej, Stephen A.; Hockerman, Susan L.; DeCrescenzo, Gary A.; McDonald, Joseph J.; Munie, Grace E.; Fletcher, Theresa R.; Stehle, Nathan; Swearingen, Craig; and Becker, Daniel. MMP-13 Selective Isonipecotamide Alpha-sulfone Hydroxamates. Bioorganic & Medicinal Chemistry Letters, 20, 12: 3561-3564, 2010. Retrieved from Loyola eCommons, Chemistry: Faculty Publications and Other Works, http://dx.doi.org/10.1016/j.bmcl.2010.04.111
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Copyright Statement
© 2010 Elsevier
Comments
Author Posting © Elsevier, 2010. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution. The definitive version was published in Bioorganic & Medicinal Chemistry Letters , Volume 20, Issue 12, June 15, 2010. http://dx.doi.org/10.1016/j.bmcl.2010.04.111