Presenter Information

Riddhi PatelFollow

Major

Biology

Anticipated Graduation Year

2021

Access Type

Open Access

Abstract

This study was conducted to determine the effect of packed red blood cell (pRBC) transfusions on hemodynamic parameters in pediatric patients with single ventricle physiology. This study was a retrospective chart review. Final analysis included data from 33 eligible patients less than 18 years of age who received a pRBC transfusion following a Norwood operation. Hemodynamic parameters were collected within a 3-hour period before and after transfusion. Hemoglobin (p<0.01) was significantly increased while arterial lactate (p=0.03) and paO2/FiO2 (p=0.04) significantly decreased following the pRBC transfusion. pRBC transfusions can improve hemodynamics and delivery of oxygen in infants with single ventricle physiology.

Community Partners

Advocate Children's Hospital

Faculty Mentors & Instructors

Dr. Michael Grillo, PhD, Assistant Professor, Department of Biology

Supported By

Dr. Rohit Loomba, MD, Attending Physician Pediatric Cardiac Intensive Care Unit, Advocate Children's Hospital

Streaming Media

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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The Acute Effect of Packed Red Blood Cell Transfusion on the Partial Pressure of Carbon Dioxide and Oxygen in Mechanically Ventilated Children After the Norwood Operation

This study was conducted to determine the effect of packed red blood cell (pRBC) transfusions on hemodynamic parameters in pediatric patients with single ventricle physiology. This study was a retrospective chart review. Final analysis included data from 33 eligible patients less than 18 years of age who received a pRBC transfusion following a Norwood operation. Hemodynamic parameters were collected within a 3-hour period before and after transfusion. Hemoglobin (p<0.01) was significantly increased while arterial lactate (p=0.03) and paO2/FiO2 (p=0.04) significantly decreased following the pRBC transfusion. pRBC transfusions can improve hemodynamics and delivery of oxygen in infants with single ventricle physiology.