Presentation Title
Investigation of Gödel-Type Coding of Protein Primary Structures
Major
Neuroscience
Anticipated Graduation Year
2021
Access Type
Open Access
Abstract
Our research explores alternative coding methods for protein primary structures. The motivation is to illuminate structure/function properties that are otherwise obscure using the traditional coding methods. The methodology makes appeal to Gödel-type coding. Critically, it offers up to 20! (≈ 2.418) expressions for a single primary structure. Such numbers vastly exceed those of database archives. To diversify our results, we randomized the amino acid alphabets by placing the overall principle of Gödel’s coding into a program. We focused on the E3 ubiquitin ligase known as MDM2. We specifically used this protein to assess one that is considered a druggable protein.
Faculty Mentors & Instructors
Daniel J. Graham, Dr., Chemistry Department
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Investigation of Gödel-Type Coding of Protein Primary Structures
Our research explores alternative coding methods for protein primary structures. The motivation is to illuminate structure/function properties that are otherwise obscure using the traditional coding methods. The methodology makes appeal to Gödel-type coding. Critically, it offers up to 20! (≈ 2.418) expressions for a single primary structure. Such numbers vastly exceed those of database archives. To diversify our results, we randomized the amino acid alphabets by placing the overall principle of Gödel’s coding into a program. We focused on the E3 ubiquitin ligase known as MDM2. We specifically used this protein to assess one that is considered a druggable protein.