Major
Neuroscience
Anticipated Graduation Year
2022
Access Type
Restricted Access
Abstract
The development of the nervous system depends heavily on glial cells, but there are many questions regarding the mechanisms underlying glial development. Previous studies have identified a transmembrane protein, Raw, as a negative regulator of the JNK signaling pathway during glial development. Raw has been observed to physically and genetically interact with Tricornered (Trc), an NDR family kinase, in neurons, which raises the question of whether or not this is true in glia.
Faculty Mentors & Instructors
Dr. Mierisch
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
The Role of Trc in Glial Development
The development of the nervous system depends heavily on glial cells, but there are many questions regarding the mechanisms underlying glial development. Previous studies have identified a transmembrane protein, Raw, as a negative regulator of the JNK signaling pathway during glial development. Raw has been observed to physically and genetically interact with Tricornered (Trc), an NDR family kinase, in neurons, which raises the question of whether or not this is true in glia.