Major
Chemistry
Anticipated Graduation Year
2022
Access Type
Open Access
Abstract
Metal-catalyzed C-H activation and functionalization have become a widely researched method in synthetic organic chemistry, with a large but largely untapped potential for pharmaceutical and medicinal applications. Challenges remain, in particular with regard to regioselectivity, since C-H bonds are ubiquitous in organic compounds. The goal of this project is to use FTIR spectroscopy as a tool with high sensitivity and time-resolution to study the mechanism of synthesized C-H activation reactions.
Faculty Mentors & Instructors
Dr. Joerg Zimmermann, Associate Professor, Department of Chemistry and Biochemistry; Sophi Todtz, Chemistry PhD Candidate, Department of Chemistry; Dr. James J. Devery, Associate Professor, Department of Chemistry
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Synthesis and Mechanistic Study of Mild-Mediated C-H Metal Activation Reactions
Metal-catalyzed C-H activation and functionalization have become a widely researched method in synthetic organic chemistry, with a large but largely untapped potential for pharmaceutical and medicinal applications. Challenges remain, in particular with regard to regioselectivity, since C-H bonds are ubiquitous in organic compounds. The goal of this project is to use FTIR spectroscopy as a tool with high sensitivity and time-resolution to study the mechanism of synthesized C-H activation reactions.