Presentation Title

Uncovering the Neural Circuitry of SIFa-regulated Rhythmic Feeding Behaviors

Presenter Information

Ariel StepankovskayaFollow

Major

Neuroscience

Anticipated Graduation Year

2022

Access Type

Open Access

Abstract

SIFamide is a neuropeptide in the fruit fly that has been found to be necessary for regulating normal feeding rhythms. However, a question that still remains is exactly where it binds to mediate feeding rhythms. Using tools like RNAi, qPCR, and FLIC, our lab is using a temperature-sensitive and intersectional approach to find where SIFa receptor expression is necessary for normal feeding rhythms. Pending qPCR results, it appears that SIFa receptor expression is not required in the ventral nerve cord and central brain for normal feeding rhythms, suggesting that SIFa is binding outside the neurons to mediate feeding rhythms.

Faculty Mentors & Instructors

Daniel Cavanaugh, PhD, Biology Department

Streaming Media

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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Uncovering the Neural Circuitry of SIFa-regulated Rhythmic Feeding Behaviors

SIFamide is a neuropeptide in the fruit fly that has been found to be necessary for regulating normal feeding rhythms. However, a question that still remains is exactly where it binds to mediate feeding rhythms. Using tools like RNAi, qPCR, and FLIC, our lab is using a temperature-sensitive and intersectional approach to find where SIFa receptor expression is necessary for normal feeding rhythms. Pending qPCR results, it appears that SIFa receptor expression is not required in the ventral nerve cord and central brain for normal feeding rhythms, suggesting that SIFa is binding outside the neurons to mediate feeding rhythms.