Major
Biology
Anticipated Graduation Year
2023
Access Type
Open Access
Abstract
This project's goal was to identify the role of Hedgehog signaling during hemipene development in the lizards Anolis sagrei. Hemepenes are the paired genitalia of squamates, lizards and snakes. When compared to mammals, there little known about the details of lizard genital development. Based on prior observations in mammals, we hypothesized that Sonic hedgehog (Shh) contributes to the development of hemipenes. We knocked down Hedgehog signaling during hemipene patterning to assess the function of Shh during hemipene development. Preliminary data demonstrate that Shh is critical for hemipene patterning in lizards.
Faculty Mentors & Instructors
Dr. Thomas Sanger
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
The Role of Hedgehog Signaling During Hemipene Development in Anolis sagrei
This project's goal was to identify the role of Hedgehog signaling during hemipene development in the lizards Anolis sagrei. Hemepenes are the paired genitalia of squamates, lizards and snakes. When compared to mammals, there little known about the details of lizard genital development. Based on prior observations in mammals, we hypothesized that Sonic hedgehog (Shh) contributes to the development of hemipenes. We knocked down Hedgehog signaling during hemipene patterning to assess the function of Shh during hemipene development. Preliminary data demonstrate that Shh is critical for hemipene patterning in lizards.