Major
Neuroscience
Anticipated Graduation Year
2023
Access Type
Open Access
Abstract
Magnetic stimulation is widely used for clinical neuromodulation, such as transcranial magnetic stimulation and peripheral nerve stimulation. Normally, neurons are expected to resume pre-stimulation states and functions immediately after the magnetic stimulation. However, the effects of magnetic stimulation still last after the termination of the magnetic stimulation (named “carry-over" effects) and could generate profound outcomes in clinical magnetic stimulation. Using experimental and modeling methods, we investigate cellular and molecular mechanisms of carry-over effects during magnetic stimulation. Delineating these mechanisms is essential for the further development of the magnetic stimulation technology for quick, reversible neuromodulation.
Faculty Mentors & Instructors
Dr. Hui Ye, associate professor, biology department; Vincent Hall, graduted luc student, neuroscience; Jenna Hendee, graduated luc student, neuroscience
Supported By
National Institute of Neurological Disorders and Stroke of the National Institutes of Health
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
"Carry-Over" Effects After Magnetic Stimulation - A Mechanistic Study
Magnetic stimulation is widely used for clinical neuromodulation, such as transcranial magnetic stimulation and peripheral nerve stimulation. Normally, neurons are expected to resume pre-stimulation states and functions immediately after the magnetic stimulation. However, the effects of magnetic stimulation still last after the termination of the magnetic stimulation (named “carry-over" effects) and could generate profound outcomes in clinical magnetic stimulation. Using experimental and modeling methods, we investigate cellular and molecular mechanisms of carry-over effects during magnetic stimulation. Delineating these mechanisms is essential for the further development of the magnetic stimulation technology for quick, reversible neuromodulation.