Major
Biology
Anticipated Graduation Year
2023
Access Type
Open Access
Abstract
Past research has demonstrated that the transcription factor Ribbon (Rib) plays an essential role in Drosophila testis development and function, but its transcriptional targets were previously unknown. Gene expression levels of rib overexpression flies were compared to the control (and results were filtered), resulting in the identification of 301 potential targets. Of these genes, approximately 20 potential targets were selected for additional analysis due to their implications in cell adhesion or the cytoskeleton, which are known functions of Rib. Follow-up experiments are currently being conducted to validate select genes of interest as targets of Rib.
Faculty Mentors & Instructors
Jennifer Mierisch, Associate Professor, Department of Biology
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Identification of Ribbon Transcriptional Targets in the Adult Drosophila Testis
Past research has demonstrated that the transcription factor Ribbon (Rib) plays an essential role in Drosophila testis development and function, but its transcriptional targets were previously unknown. Gene expression levels of rib overexpression flies were compared to the control (and results were filtered), resulting in the identification of 301 potential targets. Of these genes, approximately 20 potential targets were selected for additional analysis due to their implications in cell adhesion or the cytoskeleton, which are known functions of Rib. Follow-up experiments are currently being conducted to validate select genes of interest as targets of Rib.
Comments
Christine Severude did not present, but they are a co-author of this project.