Presenter Information

Kristen RoseFollow

Major

Neuroscience

Anticipated Graduation Year

2024

Access Type

Open Access

Abstract

Past studies have shown optogenetic excitation of Laterodorsal Tegmental Nucleus (LDTg) inputs to the Ventral Tegmental Area (VTA) is reinforcing in rats and in mice. Here we tested whether excitation of afferent inputs to the LDTg arising from the Prelimbic Cortex (PrL), the Infralimbic Cortex (IL), or the Lateral Hypothalamus (LH) is reinforcing in rats. Results will allow us to better define the brain's reward circuitry.

Faculty Mentors & Instructors

Stephan Steidl Ph.D., Associate professor, Department of Psychology

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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Investigating the Reinforcing Effects of Stimulating PrL, IL, and LH Inputs to the LDTg in Rats

Past studies have shown optogenetic excitation of Laterodorsal Tegmental Nucleus (LDTg) inputs to the Ventral Tegmental Area (VTA) is reinforcing in rats and in mice. Here we tested whether excitation of afferent inputs to the LDTg arising from the Prelimbic Cortex (PrL), the Infralimbic Cortex (IL), or the Lateral Hypothalamus (LH) is reinforcing in rats. Results will allow us to better define the brain's reward circuitry.