Presenter Information

Maria Elena SteilingFollow

Major

Biology

Anticipated Graduation Year

2026

Access Type

Restricted Access

Abstract

E. coli is responsible for urinary tract infections and symptoms. Recently, Lactobacillus species have been used to help prevent or mitigate urinary tract infections. It is known that Lactobacillus impacts the growth of E. coli, however, the exact means by which this occurs hasn't been explored fully. This project explores the impact of multiple species of Lactobacillus cell-free supernatant on liquid cultures of E. coli. The project details the exploration of Lactobacillus metabolites, and their possible ability to induce temperate bacteriophages. The project also led to sequencing of several Lactobacillus strains and publication of their genomes into research databases.

Faculty Mentors & Instructors

Catherine Putonti

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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Lactobacillus and E. coli phage interactions in the female urinary microbiome

E. coli is responsible for urinary tract infections and symptoms. Recently, Lactobacillus species have been used to help prevent or mitigate urinary tract infections. It is known that Lactobacillus impacts the growth of E. coli, however, the exact means by which this occurs hasn't been explored fully. This project explores the impact of multiple species of Lactobacillus cell-free supernatant on liquid cultures of E. coli. The project details the exploration of Lactobacillus metabolites, and their possible ability to induce temperate bacteriophages. The project also led to sequencing of several Lactobacillus strains and publication of their genomes into research databases.