Major
Biology
Anticipated Graduation Year
2026
Access Type
Restricted Access
Abstract
E. coli is responsible for urinary tract infections and symptoms. Recently, Lactobacillus species have been used to help prevent or mitigate urinary tract infections. It is known that Lactobacillus impacts the growth of E. coli, however, the exact means by which this occurs hasn't been explored fully. This project explores the impact of multiple species of Lactobacillus cell-free supernatant on liquid cultures of E. coli. The project details the exploration of Lactobacillus metabolites, and their possible ability to induce temperate bacteriophages. The project also led to sequencing of several Lactobacillus strains and publication of their genomes into research databases.
Faculty Mentors & Instructors
Catherine Putonti
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Lactobacillus and E. coli phage interactions in the female urinary microbiome
E. coli is responsible for urinary tract infections and symptoms. Recently, Lactobacillus species have been used to help prevent or mitigate urinary tract infections. It is known that Lactobacillus impacts the growth of E. coli, however, the exact means by which this occurs hasn't been explored fully. This project explores the impact of multiple species of Lactobacillus cell-free supernatant on liquid cultures of E. coli. The project details the exploration of Lactobacillus metabolites, and their possible ability to induce temperate bacteriophages. The project also led to sequencing of several Lactobacillus strains and publication of their genomes into research databases.