Major
Biology
Anticipated Graduation Year
2024
Access Type
Open Access
Abstract
This project explores the complex relationships between antibiotic resistance, nutrient limitation, and bacterial adaptation, focusing on E. coli. Antibiotic resistance poses significant challenges to public health. Nutrient limitation plays a crucial role in shaping E. coli’s ability to adapt and develop resistance against ampicillin. The Antibiotic Microbial Experiment (AME) provides valuable insights into bacterial adaptation dynamics over extended periods. I used growth curves to analyze bacterial growth kinetics and the differential effects of antibiotic concentrations on the evolved bacteria. The findings from this project give insight to the trade-offs E. coli populations exhibit when coping with antibiotic stressors.
Faculty Mentors & Instructors
Dr. Caroline Turner, Assistant Professor, Department of Biology
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Ampicillin resistance dynamics and adaptation in evolved E. coli populations
This project explores the complex relationships between antibiotic resistance, nutrient limitation, and bacterial adaptation, focusing on E. coli. Antibiotic resistance poses significant challenges to public health. Nutrient limitation plays a crucial role in shaping E. coli’s ability to adapt and develop resistance against ampicillin. The Antibiotic Microbial Experiment (AME) provides valuable insights into bacterial adaptation dynamics over extended periods. I used growth curves to analyze bacterial growth kinetics and the differential effects of antibiotic concentrations on the evolved bacteria. The findings from this project give insight to the trade-offs E. coli populations exhibit when coping with antibiotic stressors.