Major
Neuroscience
Anticipated Graduation Year
2025
Access Type
Open Access
Abstract
The human microbiome, composed of bacteria, fungi, and viruses, is influenced by diet, health, and the environment, impacting immune response, digestion, and mental health. This study analyzed microbiome data from CTCL patients, focusing on changes after phototherapy. Using Microbiome Analyst, we identified 32 significant enzymes and 8 pathways. Notably, enzyme EC:1.1.1.370 and pathway P562 increased post-phototherapy, indicating metabolic shifts in inositol processing. These findings suggest phototherapy may modulate microbial metabolism, warranting further research.
Faculty Mentors & Instructors
Dr. Michael Burns, PhD, Associate Professor, Department of Biology
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Assessing Functional Changes in the Gut Microbiome in CTCL Patients Pre- and Post Therapy
The human microbiome, composed of bacteria, fungi, and viruses, is influenced by diet, health, and the environment, impacting immune response, digestion, and mental health. This study analyzed microbiome data from CTCL patients, focusing on changes after phototherapy. Using Microbiome Analyst, we identified 32 significant enzymes and 8 pathways. Notably, enzyme EC:1.1.1.370 and pathway P562 increased post-phototherapy, indicating metabolic shifts in inositol processing. These findings suggest phototherapy may modulate microbial metabolism, warranting further research.
