Presenter Information

Vraj PatelFollow

Major

Chemistry

Anticipated Graduation Year

2021

Access Type

Open Access

Abstract

The microbiome is a dynamic ecosystem with multiple regulatory properties that influence physiological responses. We hypothesize that curcumin, a bioactive component in turmeric known for its antitumor and anti-inflammatory properties, influences changes in the gut identity which leads to the beneficial effects. However, the microbiome does not exist in isolation and is constantly interacting with and influencing the adjacent epithelial cells and the body as a whole. We will also be observing the changes in the cells’ proliferation and movement of the intestinal epithelial cells.

Faculty Mentors & Instructors

Dr. Michael Burns, Assistant Professor in Biology department at LUC; Dr. Jordan Beach, Assistant Professor at Cell and Molecular Physiology at LUMC

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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Title: The Effect of Curcumin on the human gut epithelium and resident microbiota

The microbiome is a dynamic ecosystem with multiple regulatory properties that influence physiological responses. We hypothesize that curcumin, a bioactive component in turmeric known for its antitumor and anti-inflammatory properties, influences changes in the gut identity which leads to the beneficial effects. However, the microbiome does not exist in isolation and is constantly interacting with and influencing the adjacent epithelial cells and the body as a whole. We will also be observing the changes in the cells’ proliferation and movement of the intestinal epithelial cells.