Presenter Information

Nicole ApostolopoulosFollow

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Major

Neuroscience

Anticipated Graduation Year

2021

Access Type

Open Access

Abstract

This research demonstrates how high-frequency magnetic stimulation can suppress epileptiform activity in the mouse hippocampus slices by using a magnetic field generator and a magnetic coil. We overall found that the inhibition effect was seen as dependent on the frequency and duration of the magnetic stimulus. It was also found that high frequency plays a significant role as well. Through this research, the lab now has a platform for further investigation of cellular and molecular mechanisms of the magnetic field.

Faculty Mentors & Instructors

Dr. Hui Ye (Biology Department), Jessica Helon (student mentor)

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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Focal Suppression of Epileptiform Activity in the Hippocampus by a High-Frequency Magnetic Field

This research demonstrates how high-frequency magnetic stimulation can suppress epileptiform activity in the mouse hippocampus slices by using a magnetic field generator and a magnetic coil. We overall found that the inhibition effect was seen as dependent on the frequency and duration of the magnetic stimulus. It was also found that high frequency plays a significant role as well. Through this research, the lab now has a platform for further investigation of cellular and molecular mechanisms of the magnetic field.