Presenter Information

Manuel WiduchFollow

Major

Biology

Anticipated Graduation Year

2020

Access Type

Restricted Access

Abstract

Malaria is still one of the most devastating infectious diseases endangering half of the earth’s population and killing almost half a million each year. With no vaccine and an increasing number of resistance toward our current drugs, the need for novel compounds is necessary. As part of an international and interdisciplinary team headed by Dr. Prakasha Kempaiah at the new Center for Global Health at Loyola University Medical Center, we aim to identify novel compounds that act as an antimalarial either by itself or in combination with drugs currently in use, such as artemisinin (ART) and chloroquine.

Faculty Mentors & Instructors

Dr. Stefan Kanzok, Department of Biology, Loyola University Chicago; Dr. Yash Gupta, Department of Medicine, Loyola University Medical Center; Dr. Ravi V. Durvasula, Department of Medicine, Loyola University Medical Center; Dr. Brijesh Rathi, Department of Medicine, Loyola University Medical Center, and Department of Chemistry, Hansraj College University Enclave; Dr. Prakasha Kempaiah, Department of Medicine, Loyola University Medical Center

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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In vivo screening of novel anti-malarial therapeutic compounds 
in a malaria mouse model system

Malaria is still one of the most devastating infectious diseases endangering half of the earth’s population and killing almost half a million each year. With no vaccine and an increasing number of resistance toward our current drugs, the need for novel compounds is necessary. As part of an international and interdisciplinary team headed by Dr. Prakasha Kempaiah at the new Center for Global Health at Loyola University Medical Center, we aim to identify novel compounds that act as an antimalarial either by itself or in combination with drugs currently in use, such as artemisinin (ART) and chloroquine.