Presenter Information

Christine E. SeverudeFollow

Major

Molecular Biology

Anticipated Graduation Year

2023

Access Type

Open Access

Abstract

The insulin signaling pathway is a crucial part of glucose metabolism and homeostasis. It is widely conserved throughout eukaryotes and interacts with many other signaling pathways. This project aims to explore the relationship between network architecture and evolution rate through the analysis of the insulin signaling pathway in Drosophila species. To do so, we must have gene models for these components in each species of study. As part of the GEP, I annotated the coding spans of Tor in Drosophila biarmipes. While Tor in Drosophila melanogaster has two isoforms, my annotation shows that Drosophila biarmipes has just one Tor isoform.

Community Partners

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Faculty Mentors & Instructors

Jennifer Mierisch, Associate Professor, Department of Biology

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Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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Gene Annotation of the Insulin Signaling Pathway Across Drosophila Species

The insulin signaling pathway is a crucial part of glucose metabolism and homeostasis. It is widely conserved throughout eukaryotes and interacts with many other signaling pathways. This project aims to explore the relationship between network architecture and evolution rate through the analysis of the insulin signaling pathway in Drosophila species. To do so, we must have gene models for these components in each species of study. As part of the GEP, I annotated the coding spans of Tor in Drosophila biarmipes. While Tor in Drosophila melanogaster has two isoforms, my annotation shows that Drosophila biarmipes has just one Tor isoform.