Major
Neuroscience
Anticipated Graduation Year
2023
Access Type
Open Access
Abstract
Due to most chronic diseases being polygenic, modern geneticists are using Genome-Wide Association Studies to predict disease susceptibility. The participants in this study included 2500 adults from Ghana, South Africa, Seychelles, Jamaica, and the United States. Previous studies emphasize that 80% of the genetic data is derived from white European ancestry leading to the lack of ethnic diversity and frequent medical disparities in underrepresented groups. Our findings aim to articulate the correlation of chronotypes with cardiometabolic diseases and specifically which genes and SNPs are involved in these processes.
Community Partners
Pan-UK Biobank
Faculty Mentors & Instructors
Dr. Heather Wheeler, Associate Professor, Department of Biology
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
The genetic and environmental contributions of cardiometabolic diseases in African-origin populations
Due to most chronic diseases being polygenic, modern geneticists are using Genome-Wide Association Studies to predict disease susceptibility. The participants in this study included 2500 adults from Ghana, South Africa, Seychelles, Jamaica, and the United States. Previous studies emphasize that 80% of the genetic data is derived from white European ancestry leading to the lack of ethnic diversity and frequent medical disparities in underrepresented groups. Our findings aim to articulate the correlation of chronotypes with cardiometabolic diseases and specifically which genes and SNPs are involved in these processes.