Major
Biology
Anticipated Graduation Year
2023
Access Type
Open Access
Abstract
Increasing antibiotic resistance is an important issue that impacts health and wellness. In a long-term evolution experiment, it was found that Escherichia coli grown in the absence of antibiotics over multiple generations were less resistant than their ancestors. We conducted minimal inhibitory concentration tests with different antibiotics to test how evolutionary history and nutrient limitation affect antibiotic resistance. We found that evolutionary history does impact resistance but nutrient limitation does not.
Faculty Mentors & Instructors
Dr. Caroline Turner, Assistant Professor of Biology
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
The Impact of Evolutionary History and Nutrient Limitation on LTEE E. coli Strains
Increasing antibiotic resistance is an important issue that impacts health and wellness. In a long-term evolution experiment, it was found that Escherichia coli grown in the absence of antibiotics over multiple generations were less resistant than their ancestors. We conducted minimal inhibitory concentration tests with different antibiotics to test how evolutionary history and nutrient limitation affect antibiotic resistance. We found that evolutionary history does impact resistance but nutrient limitation does not.