Major
Molecular Biology
Anticipated Graduation Year
2023
Access Type
Restricted Access
Abstract
The thioredoxin (Trx) system is a central biochemical pathway that regulates different aspects of cellular mechanisms in all organisms. We recently identified Phosducin-like-protein 3 (PhLP3) in Drosophila which plays a key role in sperm development. We hypothesize that PhLP3 is regulated by the Trx system. Investigations into the fruit fly database have revealed two germline-specific thioredoxin proteins. We hypothesize that the novel germline-specific protein called PhLP3 which is involved in sperm development may be regulated by the thioredoxin system. Here I characterized the two novel thioredoxin proteins TrxT and Dhd.
Faculty Mentors & Instructors
Dr. Stefan Kanzok; Manny Widuch Department of Biology
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Characterizing TrxT and Dhd in the Drosophila melanogaster fruit fly
The thioredoxin (Trx) system is a central biochemical pathway that regulates different aspects of cellular mechanisms in all organisms. We recently identified Phosducin-like-protein 3 (PhLP3) in Drosophila which plays a key role in sperm development. We hypothesize that PhLP3 is regulated by the Trx system. Investigations into the fruit fly database have revealed two germline-specific thioredoxin proteins. We hypothesize that the novel germline-specific protein called PhLP3 which is involved in sperm development may be regulated by the thioredoxin system. Here I characterized the two novel thioredoxin proteins TrxT and Dhd.