Major
Chemistry
Anticipated Graduation Year
2024
Access Type
Open Access
Abstract
Examining gene conversation across many species is an important tool for observing divergence patterns in vital cellular processes. The main goal of this project, which contributes to the Genomics Education Partnership Pathways Project, is to determine how well members of the insulin pathway are conserved across Drosophila species. Drosophila persimilis, the primary species investigated in this project, diverged from the melanogaster group about 25 mya, implying increased divergence between D. melanogaster and D. persimilis. Using synteny to the well-characterized D. melanogaster genome and D. persimilis sequencing data, we were able to map the likely location of Akt in D. persimilis. We are currently investigating the conservation of Akt in additional Drosophila species.
Faculty Mentors & Instructors
Jennifer Mierisch
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Gene Annotation of Akt in Drosophila persimilis
Examining gene conversation across many species is an important tool for observing divergence patterns in vital cellular processes. The main goal of this project, which contributes to the Genomics Education Partnership Pathways Project, is to determine how well members of the insulin pathway are conserved across Drosophila species. Drosophila persimilis, the primary species investigated in this project, diverged from the melanogaster group about 25 mya, implying increased divergence between D. melanogaster and D. persimilis. Using synteny to the well-characterized D. melanogaster genome and D. persimilis sequencing data, we were able to map the likely location of Akt in D. persimilis. We are currently investigating the conservation of Akt in additional Drosophila species.