Major
Molecular Biology
Anticipated Graduation Year
2025
Access Type
Open Access
Abstract
Malaria kills over half a million people yearly. My project aims to discover the extent to which the parasite remains stable in cold temperatures. The protozoan malaria parasite Plasmodium maintains its cellular shape with a network of cytoskeletal structures under its plasma membrane known as the subpellicular complex. Microtubules play a key part in this stabilizing complex. The microtubule proteins SPM-1 and TrxL-1 are hypothesized to form stabilization complexes inside the microtubules for regulation and structural reinforcement. My project investigates the role of SPM-1 in microtubule stabilization throughout varying temperatures.
Faculty Mentors & Instructors
Dr.Stefan Kanzok, Ph.D., Department of Biology
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Investigating the Stabilization Degree in Cold Temperatures of the Microtubule Associated Protein SPM-1 of the Malaria Parasite Plasmodium.
Malaria kills over half a million people yearly. My project aims to discover the extent to which the parasite remains stable in cold temperatures. The protozoan malaria parasite Plasmodium maintains its cellular shape with a network of cytoskeletal structures under its plasma membrane known as the subpellicular complex. Microtubules play a key part in this stabilizing complex. The microtubule proteins SPM-1 and TrxL-1 are hypothesized to form stabilization complexes inside the microtubules for regulation and structural reinforcement. My project investigates the role of SPM-1 in microtubule stabilization throughout varying temperatures.