Presenter Information

Allison LuedersFollow

Major

Molecular and Cellular Biochemistry Program

Anticipated Graduation Year

2022

Access Type

Open Access

Abstract

The alarming prevalence of heavy metals in the environment necessitates examining how these toxic substances impact physiological health. This project seeks to analyze how concentrations of heavy metals relate to eye cataracts. Elemental detection of eye cataract samples is performed using Graphite Furnace Atomic Absorption Spectroscopy (GFAAS) and Total Reflection X-Ray Fluorescence (TXRF) Spectrometry. Confirmation of the established GFAAS method will be performed using chromium, a potentially toxic trace element. Spectral detection of heavy metals will then begin on yeast cells, and a selectivity study will examine how the presence of alternative trace elements may interfere with GFAAS chromium detection.

Faculty Mentors & Instructors

Michelle Lund, Graduate Student, Department of Chemistry and Biochemistry; Dr. Martina Schmeling, Associate Professor, Department of Chemistry and Biochemistry

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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Spectral Detection of Elemental Chromium in Biological Samples

The alarming prevalence of heavy metals in the environment necessitates examining how these toxic substances impact physiological health. This project seeks to analyze how concentrations of heavy metals relate to eye cataracts. Elemental detection of eye cataract samples is performed using Graphite Furnace Atomic Absorption Spectroscopy (GFAAS) and Total Reflection X-Ray Fluorescence (TXRF) Spectrometry. Confirmation of the established GFAAS method will be performed using chromium, a potentially toxic trace element. Spectral detection of heavy metals will then begin on yeast cells, and a selectivity study will examine how the presence of alternative trace elements may interfere with GFAAS chromium detection.