Presenter Information

Henry WittichFollow

Major

Bioinformatics

Anticipated Graduation Year

2022

Access Type

Open Access

Abstract

Retrotransposons, a class of transposable elements, are characterized by their copy and paste insertion mechanism. As a result, these repetitive DNAs increase to dramatic copy numbers and dominate the genomes of most plants. Retrotransposon insertion near genes or in regulatory areas can influence gene expression by introducing or interrupting regulatory sequences. For this reason, it is beneficial to future research to annotate the location of retrotransposons whenever a new genome assembly is published. A draft assembly of white clover (Trifolium repens) has been published on the NCBI database and is currently being updated with long-read PacBio sequences, though it hasn’t yet been annotated. This project will involve the annotation of all long terminal repeating (LTR) retrotransposons in the Trifolium repens genome assembly.

Faculty Mentors & Instructors

Dr. Howard Laten

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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Genome Annotation of LTR Retrotransposon in Trifolium repens

Retrotransposons, a class of transposable elements, are characterized by their copy and paste insertion mechanism. As a result, these repetitive DNAs increase to dramatic copy numbers and dominate the genomes of most plants. Retrotransposon insertion near genes or in regulatory areas can influence gene expression by introducing or interrupting regulatory sequences. For this reason, it is beneficial to future research to annotate the location of retrotransposons whenever a new genome assembly is published. A draft assembly of white clover (Trifolium repens) has been published on the NCBI database and is currently being updated with long-read PacBio sequences, though it hasn’t yet been annotated. This project will involve the annotation of all long terminal repeating (LTR) retrotransposons in the Trifolium repens genome assembly.