Major
Biology
Anticipated Graduation Year
2022
Access Type
Open Access
Abstract
We sought to find whether orally administered SSRIs affect the microbial composition of the human microbiome. To identify how the microbial communities in the samples changed over time and treatment, the collected microbial samples were subjected to DNA extraction. The DNA were sent for marker gene amplification and next generation sequencing at the Loyola Genomics Facility. Upon receiving this data, our lab used a bioinformatic pipeline to analyze the genetic sequences of the marker genes in these microbial communities to determine what differences, if any, different concentrations of SSRIs have on the human microbiome.
Faculty Mentors & Instructors
Michael Burns, PhD, Biology Department
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Assessing Influence of SSRIs on the Human Gut Microbiome
We sought to find whether orally administered SSRIs affect the microbial composition of the human microbiome. To identify how the microbial communities in the samples changed over time and treatment, the collected microbial samples were subjected to DNA extraction. The DNA were sent for marker gene amplification and next generation sequencing at the Loyola Genomics Facility. Upon receiving this data, our lab used a bioinformatic pipeline to analyze the genetic sequences of the marker genes in these microbial communities to determine what differences, if any, different concentrations of SSRIs have on the human microbiome.